By Susan L. McElroy, Paul E. Keck Jr., Robert M. Post
Numerous antiepileptic medications (AEDs) now have regulatory symptoms for treating bipolar sickness. there's starting to be facts that AEDs normally have a number of necessary psychotropic results. This ebook is the 1st entire, clinically orientated, reference at the use of AEDs to regard a number of psychiatric problems corresponding to temper, psychotic, anxiousness, substance use, consuming, and character problems. Written through the top scientific specialists, Antiepileptic medicines to regard Psychiatric issues: is prepared via psychiatric illness for less complicated details collecting, and permits the health practitioner to exploit the textual content as a stand by myself reference is the 1st accomplished reference ebook clinically oriented to using AEDs to regard psychiatric disorders—other books have considering drug mechanisms and drug interactions
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Extra info for Antiepileptic Drugs to Treat Psychiatric Disorders (Medical Psychiatry Series)
Immediate versus deferred antiepileptic drug treatment for early epilepsy and single seizures: a randomised controlled trial. Lancet 2005; 365:2007–2013. 47. Leone MA, Solari A, Beghi E, FIRST Group. Treatment of the first tonic-clonic seizure does not affect long-term remission of epilepsy. Neurology 2006; 67(12):2227–2229. 48. Reynolds EH, Shorvon SD. Monotherapy or polytherapy for epilepsy? Epilepsia 1981; 22:1–10. 49. Mattson RH, Cramer JA, Collins JF, et al. Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures.
IT tiagabine only marginally reduces formalininduced behaviors in mice. IP ethosuximide dose-dependently ; mechanical and cold allodynia in rats. IP gabapentin dose-dependently ; mechanical allodynia and thermal hyperalgesia in mice. IP and IT gabapentin dose-dependently ; tactile allodynia in rats. PO lamotrigine and IP ethosuximide dosedependently ; mechanical allodynia in rats. References 31 31 12 16 18 22 18 22 19 28 26 22,24 a Monohydroxy metabolite of oxcarbazepine. Valpromide, valnoctamide, and diisopropylacetamide are more potent than valproic acid itself.
Eds. Antiepileptic Therapy: Advances in Drug Monitoring. New York, NY: Raven Press, 1980:213–219. 56. Perucca E. Is there a role for therapeutic drug monitoring of new anticonvulsants? Clin Pharmacokin 2000; 38:191–204. 57. Johannessen SI, Tomson T. Pharmacokinetic variability of newer antiepileptic drugs: when is monitoring needed? Clin Pharmacokin 2006; 45:1061–1075. 58. Annegers JF, Hauser WA, Elveback LR. Remission of seizures and relapse in patients with epilepsy. Epilepsia 1979; 20(6):729–737.
Antiepileptic Drugs to Treat Psychiatric Disorders (Medical Psychiatry Series) by Susan L. McElroy, Paul E. Keck Jr., Robert M. Post