By Gregory L. Holmes MD, Steven C. Schachter, Dr. Dorothee GA Kasteleijn-Nolst Trenite "MD MPH"
"The box of epilepsy and behaviour has grown significantly some time past variety of years, reflecting advances within the laboratory and hospital. Behavioral points of Epilepsy: ideas and Practice is the definitive textual content on epilepsy behavioral matters, from simple technology to scientific functions, for all neurologists, psychosocial experts, and researchers within the fields of epilepsy, neuroscience, and psychology/psychiatry.
Behavioral facets of epilepsy comprise a patient's reports in the course of seizures, his or her response in the course of and among seizures, the frequency of episodes and what could be made up our minds from the variety of seizures. With contributions via dozens of best overseas specialists, this can be the single booklet to hide all elements of this serious rising technology. grownup and pediatric sufferers, animal types, and epilepsy surgical procedure and its results are all coated in detail.
- Behavioral points of Epilepsy is the one resource for up to date info on a subject matter that has major and starting to be curiosity within the scientific neighborhood. This accomplished, authoritative textual content has a bench to bedside, strategy that covers:
- The mechanisms underlying epilepsy and behavior
- Neurophysiologic function
- Neuropsychiatric and behavioral issues in sufferers with epilepsy
- The results of remedies and surgical procedure on behavior
- Pediatric and adolescent epilepsy
- Disorders linked to epilepsy that influence behavior
- And a lot more"
Read or Download Behavioral Aspects of Epilepsy: Principles and Practice PDF
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Extra resources for Behavioral Aspects of Epilepsy: Principles and Practice
Assessing the behavioral and cognitive effects of seizures on the developing brain. Prog Brain Res 2002; 135:377–390. Sarkisian MR. Overview of the current animal models for human seizure and epileptic disorders. Epilepsy Behav 2001; 2(3):201–216. Heinrichs SC, Seyfried TN. Behavioral seizure correlates in animal models of epilepsy: a road map for assay selection, data interpretation, and the search for causal mechanisms. Epilepsy Behav 2006; 8(1):5–38. 6. 7. 8. 9. 10. Francis D, Diorio J, Liu D, Meaney MJ.
For example, there is evidence that the antiepileptic drug topiramate, designed originally as an oral hypoglycemic and approved subsequently as an anticonvulsant, is effective in producing weight loss sufficient to treat binge eating disorder, bulimia nervosa, and obesity. Topiramate is also reported to be effective in seizure reduction among patients with refractory focal epilepsy. Similarly, Rett syndrome patients show improvement in seizure control on topiramate. Moreover, patients receiving topiramate pharmacotherapy for a variety of neurologic disorders experience anorexia, body weight loss, and a reduction in body mass index (a coarse measure of adiposity).
The environmental manipulations that all decreased seizure frequency were (1) providing hyperosmotic saline as the only drinking fluid, (2) eliminating developmental contact with humans, (3) adulteration of the chow diet with fluoxetine, and (4) enriching the postweaning home cage environment. The social manipulations that modulated seizure frequency biphasically were (1) maternal cross-fostering and (2) supplemental paternal care. Values reflect percent of respective untreated control groups; the latter are exhibited at 100% seizure frequency in order to compare results drawn from six separate studies from our laboratory.
Behavioral Aspects of Epilepsy: Principles and Practice by Gregory L. Holmes MD, Steven C. Schachter, Dr. Dorothee GA Kasteleijn-Nolst Trenite "MD MPH"