Biotechnology: science, engineering, and ethical challenges - download pdf or read online

By Larry V. McIntire, Frederick B. Rudolph

ISBN-10: 0309052823

ISBN-13: 9780309052825

Biotechnology - the manipulation of the fundamental construction blocks of lifestyles - is swiftly advancing in laboratories, elevating severe concerns for scientists and nonscientists alike. Who will make a decision what's secure? Who could have entry to our own genetic details? What are the dangers? "Biotechnology" deals common motives of the elemental technological know-how and offers perception into those questions.

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The method is based on the ability to separate the two DNA strands. Because DNA strands are held together by weak forces to form a double-stranded structure, it is possible to separate the two strands. Short sequences of DNA can be made chemically and matched to the ends of each of the strands (Figure 1-5). These short sequences can also form base pairs. By using an enzyme that can recognize this structure and extend, by base pair interactions, each of the short strands, the products are two pieces of DNA that are identical to the original double-stranded DNA.

Med. 79:137-158. Jeffreys, A. , V. Wilson, S. L. Thein, D. J. Wetherall, and B. A. Ponder. 1986. DNA ''fingerprints" and segregation analysis of multiple markers in human pedigrees. Am. J. Hum. Genet. 39:11-24. Jeffreys, A. , M. Turner, and P. Debenham. 1990. The efficiency of multilocus DNA fingerprint probes for individualization and establishment of family relationships, determined from extensive casework. Am. J. Hum. Genet. 48:824-840. Lander, E. , and D. Botstein. 1986. Strategies for studying heterogeneous genetic traits in humans by using a linkage map of restriction fragment length polymorphism.

Interactions Between Universities and Industry Jerome Schultz 131 11. National Science Foundation's Perspective on University-Industry Interaction Neal Lane 147 12. Conflict of Interest in Basic Biomedical Research José E. Trías 152 13. Patents: Help or Hindrance to Technology Transfer? Rebecca Eisenberg 161 ETHICS, BEHAVIOR, AND VALUES IN SCIENCE AND SOCIETY 173 14. Ensuring the Ethical Conduct of Research: Who Is Responsible? Judith P. Swazey 175 15. Misconduct: Regulating and Investigating Scientific Research Barbara Mishkin 183 16.

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Biotechnology: science, engineering, and ethical challenges for the twenty-first century by Larry V. McIntire, Frederick B. Rudolph

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