Download PDF by C. R. Pringle (auth.), Daniel Kolakofsky (eds.): Bunyaviridae

By C. R. Pringle (auth.), Daniel Kolakofsky (eds.)

ISBN-10: 364276018X

ISBN-13: 9783642760181

ISBN-10: 3642760201

ISBN-13: 9783642760204

The Bunyaviridae characterize a really different family members of viruses which until eventually lately have been particularly poorly understood, and that are more and more very important in either drugs and biology. This ebook makes an attempt to regard all points in their biology, together with their average historical past, genetics, virion constitution and their strange pathway of intracellular meeting, the gene constitution and mechanisms of its expressions, antigenicity and pathogenesis in one quantity. As such, it fills a void within the virology literature. additionally, this quantity is well timed, because the molecular description of this family members is now nearly whole.

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They hypothesize that the proteolytic cleavage exposes G2 epitopes that can bind to receptors present on arthropod cells but missing on vertebrate cells. Definitive answers concerning the molecular basis of llidgut infection should be forthcoming in the near future. 4 Evolution of Bunyaviridae in Arbovirus Cycles Elucidation of the evolutionary potential of arboviruses is of more than academic significance. In addition to resulting in viruses with altered virulence and other characteristics, new viral phenotypes could be capable of infecting new vector species.

169 © Springer-Verlag Berlin' Heidelberg 1991 28 B. J. Beaty and C. H. Calisher their natural history. Even to describe in detail those cycles that are well defined would be impractical in the space allotted. Excellent reviews of the natural histories of viruses in the family Bunyaviridae or. specific groups of viruses in the family have been published. Notable are the series of in depth review chapters on specific groups of the family Bunyaviridae in The Arboviruses: Epidemiology and Ecology (MONATH 1988) and the books The Arthropod-borne Viruses of Vertebrates (THEILER and DOWNS 1973) and California Serogroup Viruses (CALISHER and THOMPSON 1983).

Nijhoff. Boston. pp 49-60 Calisher CH. Karabatsos N (1988) Arbovirus serogroups: definition and geographic distribution. In: Monoth TP (ed) The arboviruses: epidemiology and ecology. vol 1. CRC Press. Boca Raton. pp 19-58 Calisher CH. Gutierrez E. Francy DB. Alava AA. Muth DJ. Laznick JS (1983) Identification of hitherto unrecognised arboviruses from Ecuador: members of serogroups B. C. Bunyamwera. Patois. and Minatillian. Am J Trop Med Hyg 32: 877-885 Caplen H. Peters CJ. Bishop DHL (1985) Mutagen-directed attenuation of Rift Valley fever virus as a method for vaccine development.

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Bunyaviridae by C. R. Pringle (auth.), Daniel Kolakofsky (eds.)


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