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By Wai Yiu Cheung

ISBN-10: 0121714071

ISBN-13: 9780121714079

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Extra info for Calcium and Cell Function. Volume 7

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M. (1977). The possible involvement of phosphati­ dylinositol breakdown in the mechanism of stimulus-response coupling at receptors which control cell-surface calcium gates. Adv. Exp. Med. 83, 447-464. Micheli, R. , Jones, L. , and Creba, J. A. ( 1981 ). The stimulation of inositol lipid metabolism that accompanies calcium mobilization in stimulated cells: Defined characteristics and unanswered questions. Philos. Trans. R. Soc. London, Ser, B 296, 123-137. Mohell, N. (1984). Alpha,-adrenergic receptors in brown adipose tissue.

Specific protein kinases, activated by cAMP or DG, then phosphorylate intracellular proteins, and IP3 evokes release of calcium from intracellular pools. The phosphorylated proteins and increased cytosolic [Ca2+] then control the cell response. See text for further details. plasma membrane. The function of (1,3,4)IP3 is presently unknown. An­ other limb to the signaling pathway is provided by DG, which activates protein kinase C, and may then independently regulate intracellular events or synergize with Ca2+.

J. 232, 237-243. Cabot, M. C, and Jaken, S. (1984). Structural and chemical specificity of diradylglycerols for protein kinase C activation. Biochem. Biophys. Res. Commun. 125, 163-169. , and Jard, S. ( 1980). (3H)-Vasopressin binding to isolated rat hepatocytes and liver membranes: Regulation by GTP and relation to glycogen phosphorylase activation. J. Recepì. Res. 1, 137-168. , and Droogmans, G. (1981). Exchange characteristics of the noradrenaline-sensitive calcium store in vascular smooth muscle cells of rabbit ear artery.

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Calcium and Cell Function. Volume 7 by Wai Yiu Cheung

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